Malvika, the only Indian woman left in the singles draw, overcame Karupathevan Letshanaa of Malaysia 21-12, 21-16.
Srikanth lost 21-23, 8-21 to Korea's Chia Hao Lee, continuing his dismal run in international circuit this season.
Olympic medallist P V Sindhu is also missing in action as she recovers from an injury.
Tanisha Crasto and Dhruv Kapila outclassed Adnan Maulana and Indah Cahya Sari Jamil in straight games in the first round match.
India's hopes of winning a gold from the tennis courts is still alive with the mixed team reaching the title clash
Satwiksairaj Rankireddy and Chirag Shetty sailed to the semifinals with a straight-game win over Malaysians Junaidi Arif and Roy King Yap
Moein Shafaghi and Himanshu dished out superb performances as Tamil Thalaivas thrashed Bengal Warriorz 60-29 in their Pro Kabaddi League match in Pune on Wednesday.
Karthikeya Gulshan Kumar produced a thrilling performance
Sumit Nagal staged a grand recovery to get the better of Jason Jung of Chinese Taipei 3-6, 6-2, 6-0 and book his place in the quarter-finals of the Chennai Open ATP Challenger in Chennai on Thursday.
Indian shooter Sift Kaur Samra won her first individual ISSF World Cup gold in the women's 50m rifle 3-positions final, while Esha Singh bagged a second individual World Cup silver in Buenos Aires, Argentina.
Apart from archery, the Indians also bagged two medals in shooting.
Sindhu registered a stunning comeback win against Thailand's Phittayaporn Chaiwan
Sindhu, Lakshya win openers; Sai Praneeth loses in US Open
This was Sen's second straight defeat against Chou in less than a month.
Neeraj Chopra, on Sunday, won a gold in the Savo Games in Finland with an impressive performance, beating his Chinese Taipei rival Chao-Tsun Cheng as the duo warmed up for an Asian Games showdown.
Men's team outclassed Thailand 63-26, the women's side prevailed 54-22 in two Group A matches
India picked up their third victory in the Billie Jean King Cup as they defeated South Korea 2-1 in a Asia Oceania Group-1 tie in Changsha, China on Friday.
Sindhu squandered a game lead to lose 13-21, 21-15, 21-13 to the second seed Tai Tzu
Indian archery endured a forgettable outing at Stage 3 of the World Cup in Antalya, Turkey on Saturday, returning empty-handed in a performance that raised serious questions over team selection, preparation and mental fortitude, especially with the Asian Games just a year away.
Satwik-Chirag suffer shock defeat in opening round of Singapore Open
The Indian gymnast also secured a position in 18 competitors selected to compete in the women's all-round final which will take place on Wednesday, September 27.
Chirag Shetty and Satwiksairaj Rankireddy bagged the biggest title of their career, winning the French Open Super 750 crown with a straight-game decimation of Chinese Taipei's Lu Ching Yao and Yang Po Han in the men's doubles final in Paris on Sunday.
The former world number one duo had been sidelined from competitive action post the Paris Olympics due to Satwik's shoulder injury.
In men's doubles, Satwik and Chirag, currently ranked 15th in the world, defeated the Korean duo of Kang Min Hyuk and Kim Dong Ju 21-18, 21-10 in just 42 minutes.
India's roller skaters clinched two bronze medals in men's and women's 3000m team relay events at the Asian Games on Monday.
Star Indian shuttler Kidambi Srikanth advanced to the men's singles quarterfinals of the Macau Open Super 300 badminton tournament with a straight-game victory over compatriot Ayush Shetty in the second round in Macau on Thursday.
Prannoy will take on Rajawat in the second round.
Sindhu made short work of the world number 32, Yi Man 21-12, 21-10
B Sumeeth Reddy and Ashwini Ponnappa, however, suffered a 21-23, 21-13, 12-21 loss against Korean pair of Song hyun Cho and Lee Jung Hyun in their mixed doubles opening round.
Indian men's volleyball team on Wednesday stunned last edition silver winner South Korea in a five-set thriller to top the group and reach the knock-out stage of the Asian Games in Hangzhou.
Kidambi Srikanth, Priyanshu Rajawat and Kiran George won their respective men's singles round-of 16 matches to advance to the quarterfinals late on Thursday night.
Lakshya Sen is only the third Indian men's badminton player to reach the quarter-finals at the Olympic Games.
Indian shuttler Kidambi Srikanth opened his campaign at the Thailand Masters badminton tournament with a straight game win over Chinese Taipei's Wang Tzu Wei in Bangkok on Wednesday.
Bopanna has been ousted from the men's doubles with partner Yuki Bhambri but he is still in medal contention in the mixed doubles with Rutuja Bhosale.
In the previous edition in Jakarta, India had finished in 12th place.
Rajawat will take on eighth seed Kunlavut Vitidsarn of Thailand next.
Indian Mithun Manjunath stunned fourth seed and world number seven Kean Yew Loh of Singapore in the opening round while PV Sindhu and Kidambi Srikanth secured straight-game wins.
Indian shuttlers Satwiksairaj Rankireddy and Chirag Shetty will look to hit top gear when they cross swords against Tokyo bronze medallist Malaysian combination of Aaron Chia and Soh Wooi Yik
Lakshya Sen moved a place to world number 17, despite not competing in the last two weeks.
In the women's doubles, Treesa Jolly and Gayatri Gopichand won 21-18, 21-19 against the Dutch duo of Debora Jille and Cheryl Seinen. Treesa and Gayatri face Chinese Taipei's Hsu Ya Ching and Lin Wan Ching in the quarter-finals.